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Archiv-Übersicht     Angebot Nr. 12314

Angebotsdatum: 1. Juni 2017
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Molekularbiologie
Titel des Themas: RNA-based regulation

Institut: Molecular Cell Physiology
Adresse:
Prof. Dorothee Staiger
Universitaetsstrasse 25
33615 Bielefeld
Tel.:    Fax.:
Bundesland:
Homepage: http://www.uni-bielefeld.de/biologie/Zellphysiologie/
E-Mail Kontakt: mail

Beschreibung:  What are we looking for?
A motivated candidate to unravel RNA-based regulation genome-wide

 What do we offer?
The possibility to work in an international team; state-of-the-art methods to unravel posttranscriptional networks (RNA-seq, iCLIP, RNA affinity purification); modern lab infrastructure; participation in a doctoral degree program; the possibility for scientific exchange within the University; and possibilities for research stays abroad in the labs of international collaboration partners.

 What do you bring in?
A very good Master or Diploma degree in Biochemistry, Genetics, Molecular Biology or related topics; experience in RNA-Biology, Protein Biochemistry; basic knowledge in Bioinformatics; scientific creativity and ability to work in a team.

The position is limited to three years initially. Applications from suitably qualified handicapped persons are explicitly encouraged. The University welcomes applications from women.
Applications including CV, research interest and contact information of references (single pdf) should please be sent to
dorothee.staiger@uni-bielefeld.de within two weeks.
For informal enquiries please contact Prof. Dr. Dorothee Staiger,
Tel. ++49 521 106 5609
Methoden: RNA-seq,
iCLIP,
RNA affinity purification,
proteomics
Anfangsdatum: 1. Oktober 2017
Geschätzte Dauer: 3 J
Bezahlung: TVL13
Papers: Foley S,Gosai SJ, Wang D, Selamoglu N, Solitti AC, Köster T, Steffen A, Lyons E, Daldal F, Garcia BA, Staiger D, Deal RB, Gregory BD (2017) A global view of RNA-protein interactions reveals novel root hair cell fate regulators
Developmental Cell 41, 204-220.e5

Köster T, Marondedze C, Meyer K, Staiger D (2017) RNA-binding proteins revisited – the emerging Arabidopsis mRNA interactome
Trends in Plant Science 22, 512-526

Köster T, Meyer K, Weinholdt C, Smith LS, Lummer M, Speth C, Grosse I, Weigel D, Staiger D (2014) Regulation of pri-miRNA processing by the hnRNP-like protein AtGRP7 in Arabidopsis.
Nucleic Acids Research 42, 9925-9936.

Schmal C, Reimann P, Staiger D (2013) A Circadian Clock-Regulated Toggle Switch Explains AtGRP7 and AtGRP8 Oscillations in Arabidopsis thaliana.
PLoS Computational Biology 9, e1002986.

Nicaise V, Joe A, Jeong B, Korneli C, Boutrot F, Wested I, Staiger D, Alfano JR, Zipfel C (2013) Pseudomonas HopU1 Affects Interaction of Plant Immune Receptor mRNAs to the RNA-Binding Protein GRP7.
EMBO J 32, 701-712.
Sonstiges:

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