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Archiv-Übersicht     Angebot Nr. 12379

Angebotsdatum: 19. Juli 2017
Art der Stelle: Diplomarbeit
Fachgebiet: Biologie > Anthropologie
Titel des Themas: Yeast Molecular Biotechnology

Institut: Jacobs University Bremen, Life Sciences & Chemistry
Adresse:
Dr. rer. nat. Mathias Klein
Campus Ring 1
28759 Bremen
Tel.:    Fax.:
Bundesland:
Homepage:
E-Mail Kontakt: mail

Beschreibung: Jacobs University is a private, state-accredited, English-language research university in Bremen. We are offering Bachelor, Master or PhD programs in three focus areas: Health, Mobility and Diversity. Our principles are first class research and teaching, international diversity and transdisciplinary cooperation. As an international university we attract highly talented and open-minded students from all over the world. Currently, more than 1,200 students from 100 nations live and study on our residential campus.

Research:
Our research focuses on the improvement of yeast strains (Saccharomyces cerevisiae) for industrial biotechnology. Current projects aim at the improvement of product yield by the reduction of by-product formation, the extension of yeast's substrate spectrum in order to make use of certain (industrial) waste streams for the generation of value-added products and the improvement of cellular robustness for stresses occurring during industrial processes. We approach these questions by both rational and inverse engineering strategies exploiting the extensive toolbox nowadays available for systems metabolic engineering.

Prerequisites:
Bachelor of Science degree, excellent background in microbiology and molecular biology (preferably with regard to yeast), good written and verbal communication skills in the English language, team player with good communication skills, highly self-motivated and able to work independently, good time management skills

We offer:
Good, modern and well-organized laboratory facilities
Excellent supervision during all phases of the thesis work
Research in a truly international environment

According the university regulations the theses projects are unpaid. The candidates stay matriculated at their current university (from which they will also receive their degree) and will receive a guest status at Jacobs University in order to fulfill their research at the laboratories of Jacobs University.
Methoden: General techniques in microbiology and molecular biology for the engineering of S. cerevisiae (PCR, transformation, gene deletion, CRISPR/Cas9-based genome editing, spore dissection, real-time PCR...), analytical methods (HPLC, enzyme assays)
Anfangsdatum: 1. September 2017
Geschätzte Dauer: 9 - 12 months
Bezahlung: none
Papers:
Sonstiges:

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