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Archiv-Übersicht     Angebot Nr. 12522

Angebotsdatum: 21. Oktober 2017
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Zellbiologie
Titel des Themas: Patient Specific iPS Cells for Studying Leukemia

Institut: RWTH Aachen Medical School - Institute for Biomedical Engineering
Prof. Martin Zenke
Universitätsklinikum RWTH Aachen, Pauwelsstrasse 3
52074 Aachen
Tel.: 49 241 80 80760   Fax.: 49 241 80 82008
Bundesland: Nordrhein-Westfalen
Homepage: http://www.molcell.rwth-aachen.de
E-Mail Kontakt: mail

Beschreibung: The Institute for Biomedical Engineering, Department of Cell Biology invites applications of highly motivated individuals for a PhD student position on disease modelling of leukemia with patient specific induced pluripotent stem cells (iPS cells).

The project is embedded in the research consortium “Mesenchymal Interactions and Fibrogenic Signalling in Cancer Development: Molecular Mechanisms in Solid and Hematologic Neoplasma” funded by the Interdisciplinary Center for Clinical Research (IZKF) Aachen. The successful applicant will work in an international team and working language is English.

Qualifications and experience: The successful applicant should have experience in standard techniques of cell biology, tissue culture and molecular cloning. Willingness for teamwork and the ability to work independently are required.

The Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University study genetic programs that determine cell identity and developmental potential, with a focus on (i) hematopoietic stem cells and their differentiated progeny, and (ii) stem cell reprogramming and induction of pluripotency. For further information please see http://www.molcell.rwth-aachen.de

Applications including a cover letter, which specifically emphasizes your interest in our work, full CV and contact information of 2 referees should be sent by e-mail to eveline.mierau@rwth-aachen.de until November 15, 2017.

For questions please contact Martin Zenke, PhD, Professor of Cell Biology, Chairman, Director, martin.zenke@rwth-aachen.de

Institute for Biomedical Engineering, Department of Cell Biology
RWTH Aachen University Medical School, Pauwelsstrasse 30, 52074 Aachen, Germany

Helmholtz Institute for Biomedical Engineering, Pauwelsstrasse 20, 52074 Aachen, Germany
Methoden: The successful applicant will apply state-of-the-art and advanced techniques of cellular reprogramming and induction of pluripotency in human cells, iPS cell generation and maintenance, genome editing by CRISPR/Cas, stem cell specification and differentiation into hematopoietic cells.
Anfangsdatum: 21. Oktober 2017
Geschätzte Dauer: 3 Jahre
Bezahlung: 50-65% TV-L E13 according to qualification
Papers: For relevant publications see http://www.molcell.rwth-aachen.de/index.php/publications
Sonstiges: We particularly welcome and encourage applications from women, disabled people and ethnic minority groups, recognizing they are underrepresented across RWTH Aachen University. The principles of fair and open competition apply and appointments will be made on merit.

We are looking forward to your application!