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Archiv-Übersicht     Angebot Nr. 12554

Angebotsdatum: 13. November 2017
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Zellbiologie
Titel des Themas: 3D models of the stem cell niche to study cell-cell interactions in health and disease

Institut: Karlsruhe Institute of Technology (KIT), Institute of Functional Interfaces
Dr. rer. nat. Cornelia Lee-Thedieck
Hermann-von-Helmholtz-Platz 1
76344 Eggenstein-Leopoldshafen
Tel.:    Fax.:
Bundesland: Baden-Württemberg
Homepage: http://www.ifg.kit.edu/english/301.php
E-Mail Kontakt: mail

Beschreibung: Aim of the research of the group of stem cell¬–material-interactions is to develop artificial systems that mimic the natural environment of hematopoietic (= blood forming) stem cells, the ‘stem cell niche’ in the bone marrow. These model systems are used to understand the niche in health as well as hematological and musculoskeletal diseases. In the framework of the project “bloodANDbone” (https://www.kit.edu/kit/english/pi_2017_125_bone-marrow-models-to-study-blood-and-musculoskeletal-disorders.php), funded by the European Research Council, we are currently looking for a PhD candidate in biology. The successful candidate will study the mutual cell-cell interactions and communication in the stem cell niche in health and disease. The results of this project will be used to develop novel regenerative treatments for patients suffering from hematological or musculoskeletal diseases.
Methoden: This is an interdisciplinary project, in which methods of cell biology, chemistry, materials science, and biochemistry are applied. Innovative 3D biomaterials will be developed and used to answer fundamental biological questions.
Anfangsdatum: 1. Februar 2018
Geschätzte Dauer: 3 years
Sonstiges: Personal requirements: Applicants must have a university or master degree in the field of biology, biochemistry, biophysics or a similar field of study. In addition, the strong willingness and ability to work in a highly interdisciplinary team are expected. Experience in (stem) cell culture, biochemical methods or biomaterial development is a plus but not required.

Application: If you are interested, please send your application including a letter of motivation, CV, relevant certificates and contact details of academic referees preferably via email to Dr. Cornelia Lee-Thedieck (cornelia.lee-thedieck@kit.edu).
KIT prefers to balance the number of female and male employees. We therefore kindly ask female applicants to apply for this job. If qualified, handicapped applicants will be preferred.

Contact: Dr. Cornelia Lee-Thedieck, Karlsruhe Institute of Technology (KIT), Institute of Functional Interfaces, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany
phone: +49-(0)721-608 23588; email: cornelia.lee-thedieck@kit.edu