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Archiv-Übersicht     Angebot Nr. 12619

Angebotsdatum: 18. Januar 2018
Art der Stelle: Doktorarbeit
Fachgebiet: Humanmedizin > Neurologie
Titel des Themas: Assessment of YB-1 Dependent Oncolytic Adenovirus-Based Glioma-Virotherapy

Institut: Hertie Institut für Klinische Hirnforschung
Prof. Ulrike Naumann
Otfried-Müller-Str. 27
72076 Tübingen
Tel.: 07071-2980707   Fax.: 07071-2925150
Bundesland: Baden-Württemberg
Homepage: http://(https://www.hih-tuebingen.de/en/forschung/neurology-and-stroke/research-groups-and-foci/molecular
E-Mail Kontakt: mail

Beschreibung: You will work on a project funded for 3 years by the German Research Foundation.
 You will analyze the effects of oncolytic viruses in combination with immunotherapy in the treatment of experimental
glioblastoma in vitro and in vivo using state of the art techniques. For further information please visit our Homepage.
Methoden: cell culture, animal experiments, FACS, molecular biology (e.g. cloning, PCR, immunoblot, ELISA)
Anfangsdatum: 18. Januar 2018
Geschätzte Dauer: 3 Jahre
Bezahlung: TV-E13 (65%)
Papers: Mantwill, K, Naumann, U., Seznec, J., Girbinger, V., Lage, H. Surowiak P., Beier, C., Mittelbronn, M., Schlegel, J, Holm, P.S. 2013. YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells. Translational Med. 2013, 11:216

Naumann, U., Holm, P.S. Oncovirotherapy of glioblastoma – a kind of immunotherapy? Brain Disorders and Therapy( 2015), dx.doi.org/10.4172/2168-975X.S2-001
Sonstiges: Your profile:
Master´s or equivalent degree in biochemistry/neurosciences/molecular medicine/biology or related sciences.
Previous laboratory experience.
Experience in cell culture, molecular biology and animal handling is an asset.
Skills in immunology and a FELASA or adequate qualification will be of great advantage.
Scientific creativity and passion for discovery (methodical and biomedical).
Drive to learn and develop new methods, demonstrate initiative and responsibility, excellent team spirit.
Written and spoken English skills; German is an asset.

We offer:
Scientific and personal development opportunities in an international environment.
A good working atmosphere in a small, but dynamic and enthusiastic team.
A well equipped lab in the scientific environment of the Hertie Institute (www.hih-tuebingen.de).
The opportunity to present your data in conferences and to participate in workshops.

Applications should include:
A cover letter or brief statement explaining why you would like to join our institute/research group.
Your curriculum vitae including publication list (if available).
A copy of the highest academic degree certificate.
Two academic references.

The part-time position (65 %) is available from March 2018; the salary will be according to the German TVL (E 13). Closing date for application is March 15, 2018. Complete applications should be submitted preferably by e-mail as a single
pdf.document to ulrike.naumann@uni-tuebingen.de or alternatively by mail to:
Hertie Institut für Klinische
Hirnforschung, Molekulare Neuro-Onkologie, Prof. Dr. Ulrike Naumann, Otfried-Müller-Str. 27, 72076 Tübingen

For further technical/scientific information please contact Ulrike Naumann. Please submit copies only (loose-leaf binders or application folders are not required). The application documents will be destroyed at the end of the application