Zur Startseite von DrArbeit.de,
der deutschlandweiten Stellenbörse für Diplomarbeiten und Doktorarbeiten


Archiv - Stellenangebot


Dies ist ein Angebot aus der Datenbank von DrArbeit.de

Um die Datenbank komfortabel nach weiteren Angeboten durchsuchen zu können, klicken Sie einfach oben oder hier.

Archiv-Übersicht     Angebot Nr. 12623

Angebotsdatum: 10. Januar 2018
Art der Stelle: Diplomarbeit
Fachgebiet: Physik > Angewandte Physik
Titel des Themas: Quantification of oxygen metabolism in human brain with oxygen-17 magnetic resonance imaging

Institut: Universitätsklinikum Freiburg, Radiologie - Medizin Physik
Prof. Michael Bock
Breisacher Str. 60a
79106 Freiburg
Tel.: +49 761 270 94140   Fax.:
Bundesland: Baden-Württemberg
Homepage: http://https://www.uniklinik-freiburg.de/mr-en/research-groups/exprad.html
E-Mail Kontakt: mail

Beschreibung: Magnetic resonance imaging (MRI) is a powerful medical imaging technique for non-invasive investigation of the human body. In particular, 17O MRI allows direct quantification the oxygen metabolism in human brain. Over the recent years we have established 17O MRI technologies on our new 3 Tesla MRI system. For this, we have developed specific radiofrequency coils for 17O signal reception, MR control software (sequences) for the MRI system to acquire the 17O data, and image processing tools in combination with pharmacokinetic modelling of the signal dynamics.

In this master project, we will first apply 17O MRI to the human brain. For this, the acquisition strategy will be refined, and a reconstruction pipeline will be created. The technology will then be further expanded for use in the kidneys for ex vivo organ testing to improve the outcome kidney trans¬plan¬tations.
Methoden: For this project, we are looking for a master student candidate with the following profile:
• interest in medical physics and technology
• very good to excellent grades in Bachelor and Master courses
• programming experience (preferably in C++)
• self-responsibility and team orientation
The starting date is negotiable.
Anfangsdatum: 10. Januar 2018
Geschätzte Dauer: 12 months
Papers: Hoffmann SH et al. A measurement setup for direct 17O MRI at 7 T. Magn Reson Med 2011;66:1109–1115.
Kurzhunov D et al. Quantification of oxygen metabolic rates in human brain with dynamic 17O MRI. Magn Reson Med 2017;78:1157–67.
Kurzhunov D et al. 3D CMRO2 mapping in human brain with direct 17O MRI. Neuroimage 2017;155:612–624.