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Angebotsdatum: 9. Februar 2018
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > =============================
Titel des Themas: Nuclear mRNP Formation

Institut: International Giessen Graduate Centre for the Life Sciences
Adresse:
Frau Wagenbach
Leihgesterner Weg, 52
35392 Gießen
Tel.:    Fax.:
Bundesland: Hessen
Homepage: http://www.uni-giessen.de/ggl/overview/application
E-Mail Kontakt: mail

Beschreibung: Nuclear mRNP formation is the binding of nuclear mRNA-binding proteins (RBPs) to the mRNA, which largely occurs already co-transcriptional. By this process the mRNA is packaged into an mRNP. Binding of these RBPs to the mRNA is necessary for stability of the mRNA, nuclear mRNA export and even cytoplasmic events such as mRNA translation and degradation. Thus, nuclear mRNP formation is an essential step of gene expression. The aim of the Ph.D. thesis offered here is to elucidate how specific nuclear RBPs bind to the mRNA and thus contribute to nuclear mRNP formation and the control of gene expression. The main experimental system is the model organism S. cerevisiae, which offers a plethora of fast and advanced methods, and cell culture systems.

The Doctoral Programme consists of an experimental project combined with a three-year interdisciplinary graduate course curriculum leading to a dissertation. Seminars and courses are conducted in English; German language courses are offered for international students.

A Master´s degree or equivalent is required for admission. Information necessary for application can be found at:

http://www.uni-giessen.de/ggl/overview/application

Please submit your application using our online system before March 12, 2018. Please direct any enquiries concerning the online application procedure to the GGL Office (office@ggl.uni-giessen.de).
Methoden:
Anfangsdatum: 15. April 2018
Geschätzte Dauer: 3 years
Bezahlung:
Papers:
Sonstiges:

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