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Archiv-Übersicht     Angebot Nr. 12762

Angebotsdatum: 26. März 2018
Art der Stelle: Doktorarbeit
Fachgebiet: Humanmedizin > Pharmakologie
Titel des Themas: The role of atrial mitochondrial Calcium handling in arrhythmogenesis in patients with atrial fibrillation”

Institut: Institut für Pharmakologie und Toxikologie
Adresse:
Prof. Niels Voigt
Robert-Koch-Str. 40
37075 Göttingen
Tel.: +49 551 39 65174   Fax.: +49 551 39 65169
Bundesland: Niedersachsen
Homepage: http://www.molecular-pharmacology.de
E-Mail Kontakt: mail

Beschreibung: The role of mitochondria in the development and maintenance of atrial arrhythmias such as atrial fibrillation (AF) is currently unknown.
Methoden: You will employ state of the art electrophysiological techniques (Patch-Clamp) combined with modern imaging techniques (epifluorescence, FRET, super resolution microscopy) to address this question. You will study freshly isolated human atrial myocytes as well as human cardiomyocytes derived from induced pluripotent stem cells (iPS). The project will involve modern cell culture methods and viral infection. Based on your experiments we aim to identify new mechanism-based drug targets for the treatment of patients with AF.
Anfangsdatum: 1. Juli 2018
Geschätzte Dauer: 3 Jahre
Bezahlung: TV-L E 13 (65%)
Papers:
Sonstiges: You will have the opportunity to conduct part of your project in the partnering laboratory in London with the possibility to obtain a joint doctoral degree from the University of Göttingen and King’s College London.
The ideal candidate will be a highly motivated, team-oriented graduate student and should hold a Master’s degree or graduation from medical school or comparable qualification.

The student will be enrolled in the IRTG1816 graduate program, which is funded by the German Research Foundation (DFG) and is organized by the Heart Center, Universitätsmedizin Göttingen together with the British Heart Foundation Centre of Research Excellence, King`s College London. The program offers an excellent research environment, a comprehensive curriculum and a broad supervision and mentoring network. Further information on the program and the research group can be found on our websites: www.grk1816.med.uni-goettingen.de

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