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Archiv-Übersicht     Angebot Nr. 12810

Angebotsdatum: 18. April 2018
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Biophysik
Titel des Themas: (Bio)Physics & Time-resolved optical spectroscopy

Institut: LMU Biocenter
Adresse:
Prof. Thorben Cordes
Großhadernerstr. 2-4
82152 Planegg-Martiensried
Tel.:    Fax.:
Bundesland: Bayern
Homepage: http://www.mikrobiologie.biologie.uni-muenchen.de/forschung/ag_cordes/index.html
E-Mail Kontakt: mail

Beschreibung: The research group "Physical and synthetic biology” (AG Cordes) at LMU Munich is looking for a PhD student with a strong background in optics and spectroscopy. The student (Msc in Physics or equivalent) will establish a femtosecond transient absorption setup for spectroscopic studies of non-canonical DNA bases and photosynthetic complexes.

What we expect: You should be interested in design, construction and build-up of complex optical setups and be curious to answer mechanistic biological questions. Experience in optics, spectroscopy, programming, electronics and the will to obtain basic biology/chemistry skills are required.

The PhD project: (i) You will establish a setup for femtosecond transient absorption spectroscopy in the visible spectral range.[1] (ii) You will use this technique in combination with continuous wave spectroscopy and time-correlated single-photon counting to study the excited state dynamics of (non-canonical) DNA nucleobases[2], which are yet uncharacterized. The goal is to reveal evolutionary selection criteria, i.e., which photophysical and photochemical pathways were optimized to maintain high stability of DNA especially in the early phases of life. (iii) To obtain a better understanding of energy and electron transfer pathways you will further study spectroscopic properties of photosynthetic complexes of cyanobacteria[3], where parts of the antenna complex are not yet fully assembled. A second type of model system for this will be plant photosystems that form hybrid structures with inorganic materials[4].

What we offer: A 65% E13 position based in the Cordes lab, an interdisciplinary research group at the LMU. The project will be conducted in collaboration with partner labs at LMU in Biology (Prof. Leister & Prof. Nickelsen), Chemistry (Prof. Carell) and Physics (Prof. Zinth). During the project you have the chance to establish cutting edge optical spectroscopy techniques and tackle interesting biological questions. The successful applicant can apply for membership in LMU graduate schools to build a research network and to obtain additional education. The project should start as soon as possible but latest on 01.07.2018.

For a full application send a personal motivation letter with a summary of research experience, CV, study records, certificates and contact information of at least two referees as a single PDF to Thorben Cordes. Informal inquiries via telephone or email are welcome.
Methoden:
Anfangsdatum: 15. Mai 2018
Geschätzte Dauer: 3-4 Jahre
Bezahlung: 65% E13
Papers: [1] T.T.H. Herzog et al., Photochemical & Photobiological Sciences 12 (2013) page 1202.

[2] T. Carell et al., Angewandte Chemie 124 (2012) page 7220.

[3] R.A. Holzwarth et al., PNAS 103 (2006) page 6895.

[4] K. Peters et al., Advanced Functional Materials 26 (2016) page 6682.
Sonstiges:

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