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Archiv-Übersicht     Angebot Nr. 12865

Angebotsdatum: 1. Juni 2018
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Molekularbiologie
Titel des Themas: PhD in epigenetics, transcriptional regulation and molecular biology

Institut: Institute of Molecular Biology and Tumor Research (IMT)
Adresse:
Dr. rer. nat. Robert Liefke
Hans-Meerwein-Str. 2
35043 Marburg
Tel.:    Fax.:
Bundesland: Hessen
Homepage: http://www.imt.uni-marburg.de/liefke/
E-Mail Kontakt: mail

Beschreibung: At the Institute of Molecular Biology and Tumor Research (IMT), University of Marburg (Germany) two PhD-positions are available to study chromatin-based mechanisms of gene regulation in differentiation and malignancies.

Our laboratory aims to better understand the role of PRC2 associated factors in stem cell biology and human cancer. In particular, we want to better understand the biological role and molecular mechanisms of the novel PRC2-associated protein EPOP.

We offer a competitive, international research environment as part of the already existing chromatin research network (TRR81, Giessen/Marburg/Bad Nauheim/Rotterdam). We use a wide range of biochemical, molecular and cell biological, genetic and computational techniques and offer an international, highly motivating and interactive environment, state of the art facilities and optimal support to develop strong research skills and an academic profile.
Candidates should have a degree in biology, biochemistry, chemistry or equivalent and good knowledge in molecular biology and/or cell biology is required.
The salary is in accordance with the German public service salary scale. The working language is English and German.

Candidates should send their application as a single PDF, including a motivational letter, their CV and a list of two potential referees to:
robert.liefke@imt.uni-marburg.de
Methoden:
Anfangsdatum: 1. August 2018
Geschätzte Dauer: 3-4 Jahre
Bezahlung: TV-H
Papers: Li, H.; Liefke, R.; Jiang, J.; Kurland, J.V.; Tian, W.; Deng, P.; Zhang, W.; He, Q.; Patel, D.; Bulyk M.L.; Shi, Y.; and Wang, Z.
Polycomb-like proteins link the PRC2 complex to CpG islands.
2017, Nature, PMID: 28869966

Liefke, R; Karwacki-Neisius, V; Shi, Y
EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape.
2016, Molecular Cell, PMID: 27863226
Sonstiges:

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