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Archiv-Übersicht     Angebot Nr. 12969

Angebotsdatum: 30. Juli 2018
Art der Stelle: Doktorarbeit
Fachgebiet: Physik > Biophysik
Titel des Themas: 2 PhD postions: OPTICAL AND ELECTRICAL READOUT OF SINGLE-MOLECULE MEMBRANE PROCESSES ON NANOPORES

Institut: Universität Stuttgart und Universität Freiburg
Adresse:
Prof. Stephan Nussberger & Prof. Jan Behrends
Pfaffenwaldring 57
70569 Stuttgart
Tel.:    Fax.:
Bundesland: Baden-Württemberg
Homepage:
E-Mail Kontakt: mail

Beschreibung: Biological nanopores are an exciting new class of biosensors with main applications in single molecule DNA sequencing and single-molecule analysis. Within the Research Network »Functional Nanostructures« Baden Württemberg the Institute of Physiology of the University of Freiburg and the Institute of Biophysics of the University of Stuttgart offer two PhD positions (E13, 65%) for a three-year period to engage in the two following subjects:

DESIGN OF A MICROFABRICATED NANOPORE CHIP for tracing cellular membrane processes at single-molecule resolution using optical and electrophysiological methods

DEVELOPMENT OF MICROSTRUCTURED HYDROGEL-LIPID BILAYER ARRAYS for integration of membrane channel proteins
Methoden: For these challenging projects, we are looking for two talented and motivated students with strong interest in cell biology, membrane biophysics or chemical biology, using bottom-up integrative nanotechnology design principles. The candidates should hold a Masters Degree in Physics, Chemistry, Chemical Biology, Biochemistry or Biotechnology, Microsystems Technology or equivalent. Expertise in molecular biology (recombinant DNA techniques, protein expression and purification), chemical modification of proteins or peptides, single molecule imaging, electrophysiology and programming in MATLAB/ LabView will be an advantage, but is not a limiting factor.

Both Universities are committed to increasing the percentage of women in research and teaching and thus encourages women with adequate qualifications to apply. Disabled applicants are given preferential consideration in the event of equal qualification. Employment takes place via the Central Administration of the Universities.
Anfangsdatum: 30. Juli 2018
Geschätzte Dauer: 3 years
Bezahlung: E13 65%
Papers: • Bausewein et al. (2017) Cell 170: 693–700.
• Piguet et al. (2016) Nature Sci. Rep. 6: 38675–10.
• Talarimoghari et al. (2018). Eur. Phys. J. E, 41: 6288–6288.
• Boukhet et al. (2017) Macromol. Rapid Commun., 341, 1700680–1700686.
• Baaken et al. (2015). ACS Nano 9: 6443–6449.
• del Rio Martinez et al.(2015) Small 11: 119–125.
• Mahendran et al. (2012) Biophys. J. 102: 39-47.
Sonstiges: Applications should include:
• Curriculum vitae with your name, address, degree(s) with transcript(s) of grades, research experience, educational and employment history. Please include any awards, distinctions and publications.
• Motivation letter
• Name and e-mail address of two academic references

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