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Angebotsdatum: 25. August 2018
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Molekularbiologie
Titel des Themas: Virus-induced immunosuppression: From understanding the mechanism to the development of novel vaccines against Marek’s disease virus (MDV)

Institut: Institute of Virology, Department for Veterinary Medicine, FU Berlin
Adresse:
Dr. rer. nat. Susann Beetz
Chariteplatz 1
10117 Berlin
Tel.: +493028460160   Fax.:
Bundesland: Berlin
Homepage: http://https://www.zibi-berlin.de/application/phd-projects/index.html
E-Mail Kontakt: mail

Beschreibung: Marek’s disease virus (MDV) is a highly oncogenic alphaherpesvirus that infects chickens and causes high economic losses in poultry industry. Aside from deadly tumors, MDV causes immunosuppression (IS) that profoundly increases susceptibility of chickens to other pathogens. In addition, MDV infection reduces vaccine responses, resulting in a decreased protection of the animals against the corresponding pathogens. MDV vaccines themselves also induce IS to some extent, as such causing a dilemma between the absolute necessity of a MDV vaccination and the reduced response to other vaccines. Our goal is to apply our expertise and the techniques developed over the last several years by our European consortium to understand the basic mechanisms associated with IS and to develop novel vaccines that will significantly reduce the immunosuppressive properties.
Methoden:
Anfangsdatum: 1. Mai 2019
Geschätzte Dauer: 3 - 4 Jahre
Bezahlung: übliche Doktorandenstelle
Papers:
Sonstiges: We only accept applications though our application portal! Deadline is October 7th, 2018.
This PhD position will be implementes in our Graduate School:
ZIBI Graduate School Berlin / Research in the fields of Infection Biology and Immunology
For more information, please use our website:
https://www.zibi-berlin.de/index.html

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