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Archiv-Übersicht     Angebot Nr. 13266

Angebotsdatum: 30. Januar 2019
Art der Stelle: Doktorarbeit
Fachgebiet: Physik > Biophysik
Titel des Themas: Computational study of pulsating blood flow in the microcirculation

Institut: Biofluid Simulation and Modelling, Theoretische Physik VI
Prof. Stephan Gekle
Universitätsstr. 30
95445 Bayreuth
Tel.: 0921 55 4462   Fax.:
Bundesland: Bayern
Homepage: http://biofluid.physik.uni-bayreuth.de
E-Mail Kontakt: mail

Beschreibung: The microcirculatory network contains the smallest blood vessels which are most relevant for biological functions such as oxygen exchange or drug delivery. A fascinating phenomenon in the microcirculation is the spontaneous creation of highly pulsatile flow patterns. Such flows can appear when red blood cells temporarily get stuck at the apex of bifurcations and are then suddenly released back into the flow. This and many other related phenomena are still not fully understood.

The overall goal of this PhD project is to reach a systematic mechanistic understanding of the two-way-coupling between pulsating flow and red blood cell dynamics in the microcirculation using computer simulations in connection with experiments by our collaboration partners.

The PhD project is situated in the Theoretical Physics department and will use methods of computational fluid dynamics such as Lattice-Boltzmann and Immersed-Boundary. Simulations will be based on the existing ESPResSo code which will be extended by the prospective candidate. Analysis tools will be written by the candidate in C/C++. The required supercomputer ressources will be provided by the local computing cluster available at the University of Bayreuth as well as by projects on national supercomputing systems such as SuperMUC and JEWELS.

The successful candidate must possess a strong background in theoretical physics, numerical mathematics, computational engineering or a similar discipline. Good programming skills in C++ are required. A background in fluid mechanics is desirable, but not explicitly required. Research will be conducted in the Biofluid Simulation and Modeling group at the University of Bayreuth, Germany. Bayreuth is a medium-sized town with a fairly large student population and is situated in a beautiful natural setting between the mountains of Fränkische Schweiz and Fichtelgebirge.

For applications or further information please contact stephan.gekle@uni-bayreuth.de or see our
website biofluid.physik.uni-bayreuth.de
Anfangsdatum: 1. Juli 2019
Geschätzte Dauer: 3.5 Jahre