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Archiv-Übersicht     Angebot Nr. 13269

Angebotsdatum: 1. Februar 2019
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Sonstiges
Titel des Themas: The metabolic control of cardiovascular differentiation of embryonic stem cells

Institut: Insitute of Physiology
Adresse:
Frau Wagenbach
Leihgesterner Weg 52
35392 Gießen
Tel.:    Fax.:
Bundesland: Hessen
Homepage: http://https://www.uni-giessen.de/fbz/zentren/ggl/overview/application
E-Mail Kontakt: mail

Beschreibung: Stem cells will be used in regenerative medicine in the near future. To successfully apply stem cells in cell therapy approaches, the signaling cascades which underly formation of organotypic, terminally differentiated cells have to be investigated in detail. In the current research project we will unravel how the cell metabolism of embryonic stem cells is regulating differentiation, maturation and aging of cardiomyocytes as well as endothelial cells in newly formed blood vessels. The student in this project will learn to differentiate cardiac cells and blood vessels from pluripotent stem cells and will analyze their cellular function. He/she will investigate how the interplay between glycolysis and fatty acid oxidation regulates cardiovascular differentiation.
Methoden: Applicants should have a MSc degree in either Biology, Biotechnology or Veterinary Medicine. Knowledge in RT-PCR, Western blot, flow cytometry and cell culture techniques is desirable.
Anfangsdatum: 15. April 2019
Geschätzte Dauer: 3 years
Bezahlung: Doctoral position (50%)
Papers:
Sonstiges: Please apply via our application portal.

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