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Archiv-Übersicht     Angebot Nr. 13298

Angebotsdatum: 13. Februar 2019
Art der Stelle: Doktorarbeit
Fachgebiet: Humanmedizin > Physiologie
Titel des Themas: Cardiac Optogenetics

Institut: Physiology I, University Bonn
Prof. Philipp Sasse
Nussallee 11
53115 Bonn
Tel.:    Fax.:
Bundesland: Nordrhein-Westfalen
E-Mail Kontakt: mail

Beschreibung: The research group for “Cardiac Optogenetics” led by Prof. Dr. Philipp Sasse at the Institute of Physiology I, University of Bonn, Germany is offering

PhD positions (m/f/d) (65 %)

starting either April/May 2019 or October 2019.

The successful applicants can/will be embedded in the Research Training Group 1873 (RTG 1873) and will work the field of optogenetics, a technology taking advantage of light sensitive proteins for the manipulation of cells and organs. The lab of Prof. Sasse has applied this technology to stimulate cardiomyocytes and hearts to terminate cardiac arrhythmia as well as to manipulate GPCR signaling pathways (e.g. Bruegmann et al., Nature Methods 2010; Beiert et al., Cardiovasc Res. 2014; Bruegmann et al., J. Clin. Invest. 2016).

The proposed two new projects will eiter 1) apply the emerging technology of subcellular optogenetics to investigate microdomain signaling or 2) develop new laser-based optical stimulation devices for optogenetic identification of electrical cell-cell coupling in the intact heart.

Strong interest in scientific research and above-average motivation to manage the PhD project are expected. Very good English language skills are a prerequisite to join the English language PhD program. Previous experience with electrophysiological and imaging techniques, optics design or computational languages (C++, Arduino, LabView) are advantageous and should be specially highlighted in the cover letter and application form.

We offer salary according to the German salary scale TV-L E13, Jobticket and supplementary benefits in the public sector (pension plan according to VBL).

The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university. It aims to increase the proportion of women in areas where women are under-represented and to promote their careers in particular. It therefore urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable individuals with a certified serious disability and those of equal status are particularly welcome.

For further details and submitting applications please follow the guidelines at: https://www.grk1873.uni-bonn.de/application) and refer to the Sasse lab and/or optogenetics in the cover letter and application form.

For initial inquires and specific details on the projects, please contact Prof. Philipp Sasse (philipp.sasse@uni-bonn.de).

Application deadline: 30 March, 2019
Anfangsdatum: 1. April 2019
Geschätzte Dauer: 3 years