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Archiv-Übersicht     Angebot Nr. 13558

Angebotsdatum: 13. August 2019
Art der Stelle: Doktorarbeit / Diplomarbeit
Fachgebiet: Biologie > Anthropologie
Titel des Themas: PhD student in Biochemistry of Neurodegeneration

Institut: Luxembourg Institute of Health/IBBL
Frau virginie De Landsheer
Rue Thomas Edison 1A
1445 Strassen
Tel.:    Fax.:
Homepage: http://https://www.lih.lu/jobs/detail/phd-student-in-biochemistry-of-neurodegeneration-cl-fb-0819-12954
E-Mail Kontakt: mail

Beschreibung: The Enzymology & Metabolism Research Group (LCSB) and IBBL are looking to hire a PhD student as part of the PARK-QC DTU, an interdisciplinary doctoral training unit focusing on ‘Molecular, Organellar and Cellular Quality Control in Parkinson's disease and Other Neurodegenerative Diseases’ and involving several Luxembourgish biomedical research units.

In the collaborative project entitled ‘Search for novel PD biomarkers originating from increased molecular damage and/or deficient molecular quality control systems’, the successful PhD candidate will (establish and) analyse cellular and whole organism models of Parkinson’s disease, as well as PD patient-derived material (e.g. plasma, urine, CSF), applying Crispr/Cas9 technology, imaging-based phenotypic approaches and metabolomics techniques.

Main objectives are to find small molecule disease biomarkers and test small molecule-based therapeutic treatments on the cellular/whole organism models.

Key Skills, Experience and Qualifications

• Master degree in Biochemistry, Molecular/Cell Biology, Biotechnology, or a related discipline.
• Strong background in metabolic biochemistry and molecular/cellular biology, as well as good notions in bioinformatics.
• Previous experience with handling model organisms, mammalian cell culture, mass spectrometry and imaging techniques will be considered as important asset(s).
• Excellent English writing and speaking skills are essential

We offer
• Project funding available for up to 48 months
• Competitive remuneration; contract subject to public national security system benefits
• A dynamic, exciting and equal opportunity international research environment

Anfangsdatum: 1. Dezember 2019
Geschätzte Dauer: 3 year fixed-term contract (with possible extensio