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Archiv-Übersicht     Angebot Nr. 13678

Angebotsdatum: 3. November 2019
Art der Stelle: Doktorarbeit / Diplomarbeit
Fachgebiet: Biologie > Molekularbiologie
Titel des Themas: h.D. Position to Study Nuclear mRNA Packaging as part of an ERC-Funded Project

Institut: Institut für Biochemie
Prof. Katja Sträßer
Heinrich-Buff-Ring 17
35392 Giessen
Tel.:    Fax.:
Homepage: http://https://www.uni-giessen.de/fbz/fb08/Inst/biochem/straesser
E-Mail Kontakt: mail

Beschreibung: We are looking for highly motivated Ph.D. students to work on the ERC-funded project “Nuclear mRNA Packaging and mRNP Architecture” beginning as soon as possible. Already during transcription by RNA polymerase II the synthesized mRNA is bound by nuclear RNA-binding proteins and packaged into a messenger ribonucleoprotein particle (mRNP). This process is of prime importance for correct gene expression as it is necessary for stability and nuclear export of the mRNA and even determines cytoplasmic steps such as translation and mRNA degradation. In addition, defects in mRNP packaging lead to diseases. However, the regulation of mRNA packaging and nuclear mRNA export are not known, and, thus, will be elucidated in this project.
Methoden: We use a wide range of biochemical, molecular and cell biological, genetic and computational techniques and offer an international, highly motivating and interactive environment, state of the art facilities and optimal support to develop strong research skills and an academic profile. The salary is in accordance with the German public service salary scale.
Anfangsdatum: 1. Dezember 2019
Geschätzte Dauer: 3 - 4 Jahre
Bezahlung: according to state regulations (TVH)
Sonstiges: Applicants should possess a strong research background in biochemistry and molecular biology and an M.Sc. degree (or equivalent) in biology, molecular biology, biochemistry, genetics or a similar field. Specific knowledge in RNA biology and/or structural biology is of advantage.
To apply, please send an application letter, motivation letter, CV, transcripts of records, and contact information of at least two referees as a single PDF file to Prof. Dr. Katja Sträßer (katja.straesser@chemie.bio.uni-giessen.de).