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Archiv-Übersicht     Angebot Nr. 14364

Angebotsdatum: 2. September 2021
Art der Stelle: Doktorarbeit
Fachgebiet: Chemie > Biochemie
Titel des Themas: Unveiling ligand binding at Y receptors

Institut: Institut für Biochemie - Fakultät Lebenswissenschaften
Prof. Irene Coin
Brüderstrasse 34
04103 Leipzig
Tel.: 03419736996   Fax.:
Bundesland: Sachsen
E-Mail Kontakt: mail

Beschreibung: We look for a talented and motivated scientist for a project embedded in the CRC1423, a big research consortium focused on G protein-coupled receptors (https://research.uni-leipzig.de/sfb1423/). The project aims at understanding undisclosed details of ligand binding to Y receptors. The project is interdisciplinary and involves a wide spectrum of techniques. It involves a part in the wet lab, including mammalian cell culture, protein expression in mammalian cells, protein analysis, cellular assays, molecular biology work, peptide chemistry, and a computational part with molecular modeling and MD simulations in collaboration with our scientific partners.

In our group, we investigate protein-protein interactions in the live cell by combining chemical tools and the most modern molecular biology techniques. We use the expanded genetic code technology to incorporate crosslinking amino acids into proteins at specific sites, and we map interactions surfaces to discover regions of proximity of associated partners. We are a small group of open minded people. We care that everybody is happy with us and we guarantee a high quality supervision and support. Details about the team and our publications can be found here https://coin-lab.de/

Applicants must have a Master of Science or equivalent degree either in chemistry, biochemistry or molecular biology, and should be able to work in a team as well as independently. Professional proficiency in written and spoken English is expected.
Anfangsdatum: 1. November 2021
Geschätzte Dauer: 3 bis 4 Jahre