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Archiv-Übersicht     Angebot Nr. 14371

Angebotsdatum: 10. September 2021
Art der Stelle: Doktorarbeit
Fachgebiet: Biologie > Zellbiologie
Titel des Themas: PhD-position (m/w/d)

Institut: Institut für Biochemie & Molekularbiologie
Herr Thomas Becker
Nussallee 11
53115 Bonn
Tel.:    Fax.:
Bundesland: Nordrhein-Westfalen
E-Mail Kontakt: mail

Beschreibung: The University Hospital Bonn is a maximum care facility with a regular capacity of 1.300 beds. Our current staff of more than 8.000 performs assigned duties in research, teaching and medical treatment, including the use of advanced medical technologies, and public health care services at the highest possible level. Interested applicants will be offered a wide range of employment opportunities in a variety of fields.

At the Institute of Biochemistry and Molecular Biology, University of Bonn Medical School, Germany is available a part time (65% of 38.5 hrs./week)PhD position (m/f/d).
The position starts as soon as possible and for a period of three years, with the possibility of an extension.

Mitochondria fulfil various essential functions for the survival of eukaryotic cells. Their biogenesis and functions depend on the import of more than 1000 different proteins that are produced as precursors on cytosolic ribosomes. The translocase of the outer mitochondrial membrane (TOM complex) forms the entry gate for precursor proteins, which are subsequently sorted via dedicated protein machineries into the different mitochondrial subcompartments (Ellenrieder et al., 2019 Mol. Cell). Mitochondrial protein import is an essential process for cell survival and defects cause severe neurodegenerative diseases and cardiomyopathy. We have identified a protein quality control pathway that governs protein import into mitochondria at the TOM complex (Mårtensson et al., 2019 Nature). In this project, we will investigate the molecular mechanisms how protein entry into mitochondria is monitored.
We use highly innovative techniques in biochemistry, molecular and cell biology such as protein-protein-interaction studies, activity assays, blue native electrophoresis, cell-free protein synthesis and protein stability assays. We offer a well-equipped workspace in an active international team. The University of Bonn provides an excellent scientific research environment.

The ideal candidates will be highly motivated, team-oriented graduates with strong interests in protein biochemistry, molecular and cell biology. Experience with biochemical, cell and molecular biology techniques are advantageous. Candidates need to hold a diploma or a master’s degree in Biology, Biochemistry, Molecular Medicine, Chemistry or a related subject.

The Institute of Biochemistry and Molecular Biology offers:
- The salary will be according to the German salary scale TV-L (EG13, 65%)
- Supportive mentoring and a well-equipped laboratory
- Successful candidates will be awarded a PhD
- A “Großkundenticket” (subsidized public transport) is available
- There is also a possibility to use the day care center
- Supplementary benefits in the public sector (pension plan according to VBL)

The University of Bonn is committed to diversity and equal opportunity. It is certified as a family-friendly university. It aims to increase the proportion of women in areas where women are under-represented and to promote their careers in particular. It therefore urges women with relevant qualifications to apply. Applications will be handled in accordance with the Landesgleichstellungsgesetz (State Equality Act). Applications from suitable individuals with a certified serious disability and those of equal status are particularly welcome.

Applications should be sent as a single PDF by email to thbecker@uni-bonn.de. Applications should include a CV, certificates, transcript record, motivation letter and letter(s) of recommendation. We look forward to receiving your application until 30.09.2021 referring to the application number 431_2021.

Prof. Dr. Thomas Becker
Institute of Biochemistry and Molecular Biology
University of Bonn Medical School
Venusberg-Campus 1
53127 Bonn
Tel.: 0228-73-2900
Email: thbecker@uni-bonn.de
Anfangsdatum: 1. November 2021
Geschätzte Dauer: 3 years +