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Archiv-Übersicht     Angebot Nr. 14527

Angebotsdatum: 4. März 2022
Art der Stelle: Doktorarbeit
Fachgebiet: Humanmedizin > Pathologie
Titel des Themas: Research Scientist in translational cancer biology

Institut: Institut für Pathologie
Adresse:
Prof. Monika Hämmerle
Magdeburger Str. 14
06112 Halle (Saale)
Tel.:    Fax.:
Bundesland:
Homepage: http://https://www.medizin.uni-halle.de/forschung/nachwuchsgruppen/nwg-experimentelle-pathologie-nwg-haemmerle
E-Mail Kontakt: mail

Beschreibung: An innovative and highly motivated environment awaits you as part of a Max-Eder junior research group supported by the German Cancer Aid with the aim of understanding the role of platelets and tumor-associated thrombocytosis. Own preliminary work has shown a significant impact of platelets on tumor growth and metastasis (JCI 2016; Nature Comm 2017; Blood 2017; MCT 2017; Cancer Cell 2018), which we would like to characterize further, thereby focusing on the regulation of the tumor immune microenvironment by platelets.

For more information, please visit:

https://www.medizin.uni-halle.de/forschung/nachwuchsgruppen/nwg-experimentelle-pathologie-nwg-haemmerle
Methoden: Characterizing the role of platelets in tumor growth and metastasis in solid tumors using in vitro and in vivo experiments
- Cell culture
- Biochemical and molecular biology techniques (Western Blot, PCR, Cloning, CRISPR-Cas9, etc.)
- Immunohistochemistry, immunofluorescence
- in vivo experiments using mice
Anfangsdatum: 1. April 2022
Geschätzte Dauer: 3 years
Bezahlung:
Papers:
Sonstiges: Requirements:
• Master degree in the fields of life sciences (biochemistry, biology, or related)
• Basic skills in biochemical and molecular biology techniques (e.g. Cloning; CRISPR-Cas9)
• Basic skills in mammalian cell culture
• Experience with immunocytochemistry and immunohistochemistry is beneficial
• Experience with laboratory animals (mice) including Felasa B certificate would be of advantage
• Knowledge of different data bases (Pubmed, COSMIC, cBioportal)
• Basic understanding of “cancer biology” and statistics / bioinformatics would be preferred
• Good/excellent command of English, both spoken and written
• Innovative, independent and reliable working behavior paired with high intrinsic motivation
• Proactive team player with a readiness of mind and a strong passion for science

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