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| Angebotsdatum: |
4. März 2022
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| Art der Stelle: |
Doktorarbeit |
| Fachgebiet: |
Humanmedizin > Pathologie
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| Titel des Themas: |
Research Scientist in translational cancer biology
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| Institut: |
Institut für Pathologie
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| Adresse: |
| Prof. Monika Hämmerle |
| Magdeburger Str. 14 |
| 06112 Halle (Saale) |
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| Bundesland: |
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| Homepage: |
http://https://www.medizin.uni-halle.de/forschung/nachwuchsgruppen/nwg-experimentelle-pathologie-nwg-haemmerle
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| E-Mail Kontakt: |
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| Beschreibung: |
An innovative and highly motivated environment awaits you as part of a Max-Eder junior research group supported by the German Cancer Aid with the aim of understanding the role of platelets and tumor-associated thrombocytosis. Own preliminary work has shown a significant impact of platelets on tumor growth and metastasis (JCI 2016; Nature Comm 2017; Blood 2017; MCT 2017; Cancer Cell 2018), which we would like to characterize further, thereby focusing on the regulation of the tumor immune microenvironment by platelets.
For more information, please visit:
https://www.medizin.uni-halle.de/forschung/nachwuchsgruppen/nwg-experimentelle-pathologie-nwg-haemmerle
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| Methoden: |
Characterizing the role of platelets in tumor growth and metastasis in solid tumors using in vitro and in vivo experiments
- Cell culture
- Biochemical and molecular biology techniques (Western Blot, PCR, Cloning, CRISPR-Cas9, etc.)
- Immunohistochemistry, immunofluorescence
- in vivo experiments using mice
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| Anfangsdatum: |
1. April 2022 |
| Geschätzte Dauer: |
3 years
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| Bezahlung: |
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| Papers: |
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| Sonstiges: |
Requirements:
• Master degree in the fields of life sciences (biochemistry, biology, or related)
• Basic skills in biochemical and molecular biology techniques (e.g. Cloning; CRISPR-Cas9)
• Basic skills in mammalian cell culture
• Experience with immunocytochemistry and immunohistochemistry is beneficial
• Experience with laboratory animals (mice) including Felasa B certificate would be of advantage
• Knowledge of different data bases (Pubmed, COSMIC, cBioportal)
• Basic understanding of “cancer biology” and statistics / bioinformatics would be preferred
• Good/excellent command of English, both spoken and written
• Innovative, independent and reliable working behavior paired with high intrinsic motivation
• Proactive team player with a readiness of mind and a strong passion for science
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